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CyberKnife Comparison

Comparison of Radiosurgery Delivery Systems

CyberKnife® Gamma Knife® Other Linac Systems (Elekta Synergy®, Novalis®, Varian Trilogy®, TomoTherapy®)
Radiosurgery Dedicated Yes Yes No
Anatomic Area treatable with radiosurgical precision Whole body Brain/Skull base(minus extreme lateral) Varies
IMRT dosimetry Method Yes No Yes
IGRT Set-up Visualization Yes No Yes
Does “Conventional” Radiotherapy and/or IMRT No No Yes
Rigid Brain or Body Frame  required for radiosurgical accuracy No Yes Yes
Capable of conformally and homogeneously treating a non-spherical target volume, Greater than 3.5cm Yes No Yes
Capable of fractionated radiosurgery to better preserve critical adjacent tissue Yes No Yes
Tracks patient-induced motion with radiosurgical precision (Less than 1mm) Yes N/A Varies by method and manufacturer
Tracks spine motion with radiosurgical precision (Less than 1mm) Yes N/A No
Tracks organ induced target volume motion with radiosurgical precision (Less than 1mm) Yes N/A No
Tracks respiration induced organ motion with radiosurgical precision (Less than 1.5mm) Yes N/A No
Capable of real-time sub-millimeter translational and rotational beam adaptation to target volume motion Yes N/A No